computer not recognising connection
 

When first bought, the iriver 100 was recognised by my computer, altho only intermittently. But after successfully loading it with music, I am no longer able to get the computer to "see" when the player is connected! Obviously I cannot now transfer or change the files on the player in any way. I've tried using different USB ports, and connecting with the iriver turned on and off but no luck. Help!

You could try resetting it.

computer doesn't recognise Iriver E100
 

I've tried resetting...but still no luck. Any more suggestions?

Try change the USB mode, your best bet would be in UMS mode.

Try connecting it to an active USB-HUB.
Worked great for me!