It seems as though the most common problem--and/or the first thing that goes wrong--with the Zen Vision:M is the LCD screen becoming compromised. Many people are familiar with the dreaded lines on the screen, fuzziness, poor contrast, or worst of all--the screen doesn't even come on.
I have taken apart several of these ZVM's with screen problems, and each time its been the same thing: there were fracture lines, or a complete break, on the lower left or right corner of the screen. I took some pictures of one such ZVM to show here. My camera can't zoom in; it just gets blurry. I did the best I could with the pictures.
The fracture lines slice into the circuitry, causing the screen flaws.